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008			100312s2010 enka b 001 0 eng
010			_a 2010010826
020			_a9780470694237 (cloth)
035			_a(DNLM)101526381
040			_aDNLM/DLC _cDLC _dDLC
042			_apcc
050	0	0	_aR853.C55 _bC37 2010
060	1	0	_aWA 950 _bC321c 2010
082	0	0	_a615.507 24 CAR _222
100	1		_aCarstensen, Bendix.
245	1	0	_aComparing clinical measurement methods : _ba practical guide / _cBendix Carstensen.
260			_aChichester, West Sussex : _bJohn Wiley & Sons, _c2010.
300			_axi, 157 p. : _bill. (some col.) ; _c24 cm.
504			_aIncludes bibliographical references and index.
505	8		_a(Publisher-supplied data) 1 Introduction 2 Method comparisons 2.1 One measurement by each method 2.1.1 Prediction of one method from another 2.1.2 Why not the correlation? 2.1.3 A new method and a reference method 2.2 Replicate measurements by each method 2.2.1 Exchangeable replicates: fat data 2.2.2 Linked replicates: Oximetry data 2.2.3 Why not use the averages of the replicates? 2.3 More than two methods 2.4 Terminology and notation 2.5 What it is all about 3 How to use this chapter 3.2 Two methods 3.2.1 Single measurements 3.2.2 Comparing with a gold standard 3.2.3 Replicate measurements 3.3 More than two methods 3.3.1 Single measurements 3.3.2 Replicate measurements 4 Two methods with a single measurement on each 4.1 Model for limits of agreement 4.1.1 Prediction between methods 4.1.2 The correlation of the difference and the average 4.2 Non-constant difference between methods 4.3 A worked example 4.4 What really goes on 4.4.1 Scaling 4.4.2 Independence 4.4.3 Actual behavior 4.5 Other regression methods for non-constant bias 4.5.1 Why ordinary regression fails 4.5.2 Deming regression 4.6 Comparison with a gold standard 4.7 Non-constant variance 4.7.1 Regression approach 4.7.2 A worked example 4.8 Transformations 4.8.1 Log-transform 4.9 Summary 5 Replicate measurements 5.1 Pairing of replicate measurements 5.1.1 Exchangeable replicates 5.1.2 Linked replicates 5.2 Plotting replicate measurements 5.3 Models for replicate measurements 5.3.1 Exchangeable replicates 5.3.2 Linked replicates 5.4 Interpretation of the random effects 5.5 Estimation 5.6 Getting it wrong and getting it almost right 5.6.1 Averaging over replicates 5.6.2 Replicates as items 5.7 Summary 6 Several methods of measurement 6.1 Model 6.2 Replicate measurements 6.3 Single measurement by each method
505	8		_a7 A general model for method comparisons 7.1 Scaling 7.2 Interpretation of the random effects 7.3 Parametrization of the mean 7.4 Prediction limits 7.4.1 Mean of replicates 7.4.2 Plotting predictions between methods 7.4.3 Reporting variance components 7.4.4 Comparison with a gold standard 7.5 Estimation 7.5.1 Alternating regressions 7.5.2 Estimation using BUGS 7.5.3 A worked example 7.6 Models with non-constant variance 7.6.1 Linear dependence of residual standard error 7.7 Summary 8 Transformation of measurements 8.1 Log-transformation 8.2 Transformations of percentages 8.2.1 A worked example 8.2.2 Implementation in MethComp 8.3 Other transformations 8.3.1 Different transformations for different methods 8.4 Several methods 8.5 Variance components 8.6 Summary 9 Repeatability, reproducibility and coefficient of variation 9.1 Repeatability 9.2 Reproducibility 9.3 Coefficient of variation 9.3.1 Symmetric interval on the log-scale 9.3.2 Computing the CV correctly 9.3.3 Transformations 10 Measures of association and agreement 10.1 IBC individual bioequivalence criterion 10.2 Agreement index 10.3 Relative variance index 10.4 Total deviation index 10.5 Correlation measures 10.5.1 Correlation coefficient 10.5.2 Intraclass correlation coefficient 10.5.3 Concordance correlation coefficient 10.6 Summary 11 Design of method comparison studies 11.1 Sample size 11.1.1 Mean parameters 11.1.2 Variance parameters 11.2 Repeated measures designs 11.3 Summary 12 Examples using standard software 12.1 SAS 12.1.1 Exchangeable replicates 12.1.2 Linked replicates 12.2 Stata 12.2.1 Exchangeable replicates 12.2.2 Linked replicates 12.3 R 12.3.1 Exchangeable replicates 12.3.2 Linked replicates 13 The MethComp package for R 13.1 Data structures 13.2 Function overview 13.2.1 Graphical functions 13.2.2 Data manipulating functions 13.2.3 Analysis functions 13.2.4 Reporting functions.
520			_a"This book sets out to provide an example-based, 'how-to' guide to the comparison of measurement methods in a clinical context. Whilst much material has been published on obtaining and comparing accurate measurements in medical research this will be the first book length treatment of the subject. The author draws upon his experience in multicentre clinical studies to present data and examples drawn from real case studies. The book will be supplemented by a website hosting datasets and programs to allow the reader to reproduce all of the analyses"--Provided by publisher.
650		0	_aClinical trials _xEvaluation.
650		0	_aClinical trials _xStatistical methods.
650	1	2	_aClinical Medicine.
650	2	2	_aCase-Control Studies.
650	2	2	_aModels, Statistical.
650	2	2	_aRegression Analysis.
650	2	2	_aStatistics as Topic _xmethods.
906			_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg
942			_2ddc _cRFT