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022 _a2186-361X
100 _aKondli Nagaraj Megha
245 0 _aNarrow-band chirp and tone burst auditory brainstem response as an early indicator of synaptopathy in industrial workers exposed to occupational noise
260 _c2019
270 _aAll India Institute of Speech and Hearing, Manasagangothri
300 _a179-186
490 _vVolume 8 Issue 3
520 _aThis study aims at characterizing and comparing the findings of auditory brainstem response (ABR) using narrow-band chirp (NB-chirp) and tone burst (TB) for both latency and amplitude parameters among those exposed to occupational noise and to determine which among the two serves as a better indicator of noise-induced cochlear neuropathy. Forty adult males in the age range of 20-35 years were considered, wherein 20 of them were exposed to noise > 80 dB (A) for 8 hours per day constituting Noise-exposed group; and Control group consisted of 20 individuals without occupational noise exposure. ABR was recorded using NB-chirp and TB for four frequencies at 80 dB nHL through Etymotic Research – 3A (ER-3A) Insert phones using Interacoustics Eclipse EP-25 in individuals with and without noise exposure. MANOVA was performed to compare between TB ABR and NB-chirp ABR between the two groups. Statistical analysis revealed a notable difference for NB-chirp comparisons between the two groups at three frequencies: 500 Hz, F(1, 38) = 10.6; 1000 Hz, F(1, 38) = 7.91; and 2000 Hz, F(1, 38) = 6.64. Whereas, the difference was evident at only 500 Hz: F(1, 38) = 4.98 in case of TB ABR. However, there was no significant difference seen at any of the frequencies for amplitude parameters in both TB and NB-chirp ABR. Latency of wave V using NB-chirp was considered to be a better indicator compared to TB, acting as a better clinical tool in early identification, diagnosis, and monitoring of noise induced hearing loss (NIHL).
653 _aAuditory brainstem response, narrow band-chirp, tone burst, noise induced hearing loss, cochlear synaptopathy
700 _aAishwarya Lakshmi
700 _aKoratagere Narayanaswamy Divyashree
700 _aKunnupurath Puthenveedu Keerthana
700 _aSreeraj Konadath
700 _aSugathan Adithya
700 _aZeena Venkatacheluvaiah Pushpalatha
773 _aIntractable & rare diseases research
856 _uhttps://doi.org/10.5582/irdr.2019.01073
942 _cFJAS
_yFJAS
999 _c17929
_d17929