000			01643caa a2200169 4500
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100			_aAbhishek, B. P
245		0	_aSpeech and Language Profiling in Twins with Lowe Syndrome
260			_c2018
300			_a1-4
490			_vVolume 4 Issue 1
520			_aLowe syndrome is a very rare syndrome. The prevalence rate of this syndrome is 1 in 500,000. This syndrome is considered to be an autosomal recessive syndrome and only males are affected. Cataract is considered to be the most common symptom of this syndrome, and is manifested in the early years of child’s life. The other signs seen in children with Lowe syndrome include short stature, dental cysts, rickets, increased vulnerability to bone fractures and degenerative joint disease. Speech and language profiling has not been reported in the children with Lowe syndrome previously in literature. The present study is one such attempt to profile the speech and language deficits. Profiling was carried out on twins aged 5.8 years. The diagnosis of Lowe syndrome was done when the children were 6 months old. The elder of the twins was 3 minutes older than the younger. Profiling was carried out in terms of the phonological deficits and the linguistic deficits exhibited by these children. The younger child presented with a relatively better speech and language profile compared to the older child.
653			_achildhood cataract, language profiling, prognosis, renal problems, twins
773			_aInternational Journal of Molecular Biotechnology
856			_uhttps://doi.org/10.37628/ijmb.v4i1.272
942			_cFJAS _yFJAS
999			_c17909 _d17909