000			01984caa a2200205 4500
008			210621s9999 xx 000 0 und d
022			_a1434-4726
100			_aSuresh Chandan, H
245		0	_aAudiological changes over time in adolescents and young adults with auditory neuropathy spectrum disorder
260			_c2015
270			_aDepartment of Audiology, All India Institute of Speech and Hearing, Manasagangothri, Naimisham Campus, Mysore, 570006, Karnataka, India
270			_mhs0@purdue.edu
300			_a1801–1807
490			_vVolume 272 Issue 7
520			_aAuditory neuropathy spectrum disorder (ANSD) describes a condition in which a patient's otoacoustic emissions (OAE) are (or were at one time) present and auditory brainstem responses (ABR) are abnormal or absent. ANSD is also diagnosed based on the presence of cochlear microphonics and abnormal or absent ABRs with or without abnormalities of OAE. We noted the changes in audiological characteristics over time with respect to pure tone thresholds, OAEs and Speech Identification Scores (SIS) in seven individuals with ANSD. The results indicated that all the individuals with ANSD had decreased SIS over time, whereas there was subsequent reduction in pure tone thresholds only in nine out of fourteen ears. There was absence of OAEs for two individuals in both ears during the follow-up evaluations. There was no regular pattern of changes in pure tone thresholds or SIS across all individuals. This indicates that there may be gradual worsening of hearing abilities in individuals with ANSD. Thus, regular follow-up and monitoring of audiological changes are necessary for individuals with ANSD. Also, longitudinal studies need to be done to further add evidence to the audiological changes over time in individuals with ANSD.
700			_a Prashanth Prabhu
773			_aEuropean Archives of Oto-Rhino-Laryngology
856			_uhttps://doi.org/10.1007/s00405-015-3505-0
942			_cFJAS _yFJAS
999			_c17639 _d17639