000			02068caa a2200205 4500
008			210621s9999 xx 000 0 und d
022			_a1434-4726
100			_aPrashanth Prabhu
245		0	_aAcquired auditory neuropathy spectrum disorder after an attack of chikungunya: case study
260			_c2016
270			_aDepartment of Audiology, All India Institute of Speech and Hearing, Manasagangothri, Naimisham Campus, Mysore, 570006, Karnataka, India
270			_mprashanth.audio@gmail.com
300			_a257–261
490			_vVolume 273 Issue 1
520			_aAuditory neuropathy spectrum disorder (ANSD) is a retrocochlear disorder in which the cochlear functioning is normal but the transmission in the auditory neural pathway is affected. The present study reports of a 14-year-old teenager with acquired ANSD after an attack of chikungunya. He reported symptoms of difficulty in understanding speech, tinnitus and vertigo when exposed to loud sounds. The audiological characteristics suggested auditory neuropathy spectrum disorder with raising audiogram configuration. The results of tinnitus evaluation showed low-pitched tinnitus and it was persistent causing significant handicap to him based on self report tinnitus handicap questionnaire results. The results of depression, anxiety and stress scale also suggested symptoms of mild depression and anxiety. Chikungunya virus is suspected to be neurotropic in nature which can damage auditory nerve cells and may have caused ANSD. The result also shows presence of tullio's phenomenon and absence of cervical vestibular evoked myogenic potentials suggesting damage to the vestibular neuronal system. The possible pathophysiology of chikungunya virus causing ANSD and vestibular symptoms needs to be explored further in future studies.
653			_aAnxiety; Auditory neuropathy spectrum disorder; Chikungunya; Depression; Tinnitus; Tullio’s phenomenon.
773			_aEuropean Archives of Oto-Rhino-Laryngology
856			_uhttps://doi.org/10.1007/s00405-015-3578-9
942			_cFJAS _yFJAS
999			_c17638 _d17638