The Buxbaum, Joseph D. editor. Hof, Patrick R. editor. text bibliography ne 2013 2013 First edition. monographic eng

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xii, 480 pages : illustrations (chiefly color) ; 28 cm Section 1: Autism Spectrum Disorders 1.1 Epidemiology of autism spectrum disorders; 1.2 The behavioral manifestations of autism spectrum disorders; 1.3 Early manifestations of autism spectrum disorders; 1.4 Asperger Syndrome and Its Relationship to Autism Spectrum Disorders; 1.5 Behavioral and Psychosocial Interventions for Individuals with ASD; 1.6 Current Trends in the Pharmacological Treatment of Autism Spectrum Disorders; 1.7 Novel therapeutics in autism spectrum disorders Section 2: Etiology of Autism Spectrum Disorders 2.1 Medical genetics and autism spectrum disorders; 2.2 Copy Number Variation in Autism Spectrum Disorders; 2.3 Common genetic variants in autism spectrum disorders; 2.4 Next-Generation Sequencing for Gene and Pathway Discovery and Analysis in Autism Spectrum Disorders; 2.5 Mitochondria and Autism Spectrum Disorders; 2.6 Parental and perinatal risk factors in ASDs; 2.7 The Environment in autism spectrum disorders; 2.8 Hormonal influences in typical development: Implications for autism; 2.9 Immune abnormalities and autism spectrum disorders Section 3: Brain Imaging and Neuropatholgy of Autism Spectrum Disorders 3.1 Structural and functional MRI studies of autism spectrum disorders; 3.2 DTI and tractography in the autistic brain; 3.3 Attentional network deficits in autism spectrum disorders; 3.4 The cerebellum in autism spectrum disorders; 3.5 The amygdala in autism spectrum disorders; 3.6 Discrete cortical neuropathology in autism spectrum disorders; 3.7 The minicolumnopathy of autism spectrum disorders; 3.8 Inhibitory and excitatory systems in autism spectrum disorders; 3.9 Clinicopathological Stratification of Idiopathic Autism and Autism Associated with 15q11.2-q13 Duplications Section 4: Model Systems and Pathways in Autism Spectrum Disorders 4.1 Mouse behavioral models for autism spectrum disorders; 4.2 Nonhuman primate models for autism spectrum disorders; 4.3 Inducible pluripotent stem cells in ASDs; 4.4 A 15q11-q13 duplication mouse model for autism spectrum disorders; 4.5 Fragile X syndrome and autism spectrum disorders; 4.6 MECP2 and autism spectrum disorders; 4.7 SHANK2 and SHANK3 Mutations Implicate Glutamate Signaling Abnormalities in Autism Spectrum Disorders; 4.8 PI3K signaling and miRNA regulation in autism spectrum disorders; 4.9 Getting from 1000 genes to a triad of symptoms: The emerging role of systems biology in autism spectrum disorders [edited by] Joseph D. Buxbaum, Patrick R. Hof, Includes bibliographical references and index. Autism spectrum disorders Neurosciences Child Developmental Disorders, Pervasive RC553.A88 N536 2013 616.858 82 BOX H; 1 44.91 77.50 9780123919243 (hdbk.) 012391924X (hdbk.) 2013370264 BTCTA 130925 20200228114155.0 17898020 eng