TY - BOOK AU - Drlica,Karl TI - Understanding DNA and gene cloning: a guide for the curious SN - 0471434167 (pbk. : alk. paper) AV - QH442.2 .D75 2004 U1 - 572.86 DRL 21 PY - 2004/// CY - Hoboken, NJ PB - Wiley KW - Molecular cloning KW - Recombinant DNA KW - Genetic engineering KW - Genetics N1 - Includes bibliographical references (p. 325-335) and index; Chapter 1. Preview: Life as Interacting Molecules. PART I. BASIC MOLECULAR GENETICS. Chapter 2. Structure of DNA: Two Long, Interwound Chains. Chapter 3. Reproducing DNA: Information Transfer from One Generation to the Next. Chapter 4. Gene Expression: Cellular Use of Genetic Information. PART II. MANIPULATION DNA. Chapter 5. Microbial Growth: One-celled Organisms as Tools for Gene Cloning. Chapter 6. Plasmids and Phages: Submicroscopic Parasites Used to Deliver Genes to Cells. Chapter 7. Cutting and Joining DNA: Restriction Endonucleases and Ligases Used to Restructure DNA Molecules. Chapter 8. Using Complementary Base Pairing: Hybridization, Probes, and Amplification using PCR. Chapter 9. Cloning Genes: Isolation of a Hemoglobin Gene. Chapter 10. Using Cloned Genes: Gene Structure, Expression Vectors, and Gene Function. PART III. MODERN MOLECULAR GENETICS. Chapter 11. Beyond the Central Dogma: A Sampling of Insights Derived from Gene Cloning. Chapter 12. Retroviruses: AIDS and Gene Delivery. Chapter 13. Cancer Genes: The Loss of Growth Control. PART IV: HUMAN GENETICS. Chapter 14. Heredity: Pattern of Inheritance and Genetic Instability. Chapter 15. Application of Human Genetics: Genetic Testing, Gene Therapy, and DNA Fingerprinting. PART V. WHOLE GENOMES. Chapter 16. Genomics: Using Whole Genomes to Study Life. Additional Reading. Glossary. Abbreviations. Index UR - http://www.loc.gov/catdir/description/wiley036/2003043077.html UR - http://www.loc.gov/catdir/toc/wiley032/2003043077.html ER -