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  <titleInfo>
    <title>Understanding DNA and gene cloning</title>
    <subTitle>a guide for the curious</subTitle>
  </titleInfo>
  <name type="personal">
    <namePart>Drlica, Karl.</namePart>
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    <place>
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    <publisher>Wiley</publisher>
    <dateIssued>c2004</dateIssued>
    <dateIssued encoding="marc">2004</dateIssued>
    <edition>4th ed.</edition>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <physicalDescription>
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    <extent>xiv, 369 p. : ill. ; 23 cm.</extent>
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  <tableOfContents>Chapter 1. Preview: Life as Interacting Molecules. PART I. BASIC MOLECULAR GENETICS. Chapter 2. Structure of DNA: Two Long, Interwound Chains. Chapter 3. Reproducing DNA: Information Transfer from One Generation to the Next. Chapter 4. Gene Expression: Cellular Use of Genetic Information. PART II. MANIPULATION DNA. Chapter 5. Microbial Growth: One-celled Organisms as Tools for Gene Cloning. Chapter 6. Plasmids and Phages: Submicroscopic Parasites Used to Deliver Genes to Cells. Chapter 7. Cutting and Joining DNA: Restriction Endonucleases and Ligases Used to Restructure DNA Molecules. Chapter 8. Using Complementary Base Pairing: Hybridization, Probes, and Amplification using PCR. Chapter 9. Cloning Genes: Isolation of a Hemoglobin Gene. Chapter 10. Using Cloned Genes: Gene Structure, Expression Vectors, and Gene Function. PART III. MODERN MOLECULAR GENETICS. Chapter 11. Beyond the Central Dogma: A Sampling of Insights Derived from Gene Cloning. Chapter 12. Retroviruses: AIDS and Gene Delivery. Chapter 13. Cancer Genes: The Loss of Growth Control. PART IV: HUMAN GENETICS. Chapter 14. Heredity: Pattern of Inheritance and Genetic Instability. Chapter 15. Application of Human Genetics: Genetic Testing, Gene Therapy, and DNA Fingerprinting. PART V. WHOLE GENOMES. Chapter 16. Genomics: Using Whole Genomes to Study Life. Additional Reading. Glossary. Abbreviations. Index.</tableOfContents>
  <note type="statement of responsibility">Karl Drlica.</note>
  <note>Includes bibliographical references (p. 325-335) and index.</note>
  <subject authority="lcsh">
    <topic>Molecular cloning</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Recombinant DNA</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Genetic engineering</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Genetics</topic>
  </subject>
  <classification authority="lcc">QH442.2 .D75 2004</classification>
  <classification authority="ddc" edition="21">572.86 DRL</classification>
  <identifier type="isbn">0471434167 (pbk. : alk. paper)</identifier>
  <identifier type="lccn">2003043077</identifier>
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