02380cam a22003014a 450000100090000000300040000900500170001300800410003001000170007102000350008804000180012304200080014105000230014908200190017210000180019124500820020925000120029126000340030330000340033750400640037150513920043565000230182765000210185065000250187165000140189685600900191085600780200013084830OSt20190927164335.0030206s2004    njua     b    001 0 eng    a  2003043077  a0471434167 (pbk. : alk. paper)  aDLCcDLCdDLC  apcc00aQH442.2b.D75 200400a572.86 DRL2211 aDrlica, Karl.10aUnderstanding DNA and gene cloning :ba guide for the curious /cKarl Drlica.  a4th ed.  aHoboken, NJ :bWiley,cc2004.  axiv, 369 p. :bill. ;c23 cm.  aIncludes bibliographical references (p. 325-335) and index.  aChapter 1. Preview: Life as Interacting Molecules. PART I. BASIC MOLECULAR GENETICS. Chapter 2. Structure of DNA: Two Long, Interwound Chains. Chapter 3. Reproducing DNA: Information Transfer from One Generation to the Next. Chapter 4. Gene Expression: Cellular Use of Genetic Information. PART II. MANIPULATION DNA. Chapter 5. Microbial Growth: One-celled Organisms as Tools for Gene Cloning. Chapter 6. Plasmids and Phages: Submicroscopic Parasites Used to Deliver Genes to Cells. Chapter 7. Cutting and Joining DNA: Restriction Endonucleases and Ligases Used to Restructure DNA Molecules. Chapter 8. Using Complementary Base Pairing: Hybridization, Probes, and Amplification using PCR. Chapter 9. Cloning Genes: Isolation of a Hemoglobin Gene. Chapter 10. Using Cloned Genes: Gene Structure, Expression Vectors, and Gene Function. PART III. MODERN MOLECULAR GENETICS. Chapter 11. Beyond the Central Dogma: A Sampling of Insights Derived from Gene Cloning. Chapter 12. Retroviruses: AIDS and Gene Delivery. Chapter 13. Cancer Genes: The Loss of Growth Control. PART IV: HUMAN GENETICS. Chapter 14. Heredity: Pattern of Inheritance and Genetic Instability. Chapter 15. Application of Human Genetics: Genetic Testing, Gene Therapy, and DNA Fingerprinting. PART V. WHOLE GENOMES. Chapter 16. Genomics: Using Whole Genomes to Study Life. Additional Reading. Glossary. Abbreviations. Index. 0aMolecular cloning. 0aRecombinant DNA. 0aGenetic engineering. 0aGenetics.423Publisher descriptionuhttp://www.loc.gov/catdir/description/wiley036/2003043077.html413Table of contentsuhttp://www.loc.gov/catdir/toc/wiley032/2003043077.html