Tinnitus and hyperacusis : facts, theories, and clinical implications /
Jos J. Eggermont, Department of Physiology, Pharmacoloy, and Psychology, University of Calgary, Calgary, AB, Canada.
- xix, 311 pages : illustrations (some color) ; 23 cm
Includes bibliographical references and index.
Cover image Title page Table of Contents Copyright Preface Abbreviations in the main text Chapter 1. Tinnitus, hyperacusis, and hearing loss 1.1. Introduction 1.2. Acquired hearing loss 1.3. Loudness recruitment 1.4. Noise-induced temporary threshold shifts 1.5. Noise exposure not causing PTS or TTS 1.6. Tinnitus pitch, loudness, and hearing loss 1.7. Summary Chapter 2. Epidemiology, etiology, and genetics 2.1. Prevalence of tinnitus and hyperacusis 2.2. Etiology 2.3. Genetics 2.4. Summary Chapter 3. Physiological markers of tinnitus and hyperacusis 3.1. Spontaneous neural activity. Noise or information carrier? 3.2. Spike-firing synchrony 3.3. Brain rhythms 3.4. Thalamocortical oscillations 3.5. Spike-LFP and EEG/MEG correlation and networks in human cortex 3.6. Auditory-evoked potentials 3.7. Summary Chapter 4. Substrates of tinnitus and hyperacusis in the animal auditory system 4.1. Spontaneous firing activity in general 4.2. Effects of salicylate and noise exposure in auditory pathways 4.3. Cell types and afferent pathways 4.4. Hyperacusis 4.5. Neurotransmitters, neuromodulators, and immediate early genes 4.6. Summary Chapter 5. Evoked potentials and neuroimaging in humans with tinnitus 5.1. Auditory-evoked potentials and tinnitus 5.2. Brain structure, rhythms, and networks 5.3. Brain networks in humans with tinnitus 5.4. Summary Chapter 6. Tinnitus and hyperacusis: The nonclassical auditory system 6.1. Overview of brain areas activated by sound compared to resting state 6.2. The amygdala 6.3. The hippocampus 6.4. Cingulate cortex 6.5. Human tinnitus and the limbic system 6.6. Comparison of animal and human data 6.7. Cerebellum 6.8. Summary Chapter 7. Tinnitus and the nonauditory brain 7.1. The nonauditory brain in cognition and perception 7.2. Tinnitus-related changes in structural and functional MRI networks 7.3. EEG/MEG-based network connectivity changes in tinnitus 7.4. Comparing functional connectivity changes in tinnitus and hearing loss 7.5. Connectivity changes of the nucleus accumbens 7.6. Transitions from no-tinnitus to tinnitus, and from acute to chronic tinnitus 7.7. Summary Chapter 8. Loudness recruitment and hyperacusis: the central-gain model 8.1. Hyperacusis and related symptoms 8.2. Hyperacusis in common disorders 8.3. Loudness recruitment and increased central gain 8.4. Central gain and hyperacusis 8.5. Human studies of hyperacusis 8.6. Mechanisms of hyperacusis 8.7. Summary Chapter 9. Bottom-up tinnitus models 9.1. The neural synchrony model 9.2. The cortical map reorganization and filling-in models 9.3. The maladaptive plasticity model 9.4. The central gain enhancement model and tinnitus 9.5. The insufficient central compensation model 9.6. Summary Chapter 10. Top-down tinnitus models 10.1. The Jastreboff model 10.2. The thalamocortical dysrhythmia/global workspace model 10.3. Noise cancellation by frontostriatal gating 10.4. The increased central noise model 10.5. Interacting neural network models 10.6. The sensory predictive coding or Bayesian inference model 10.7. Summary Chapter 11. Behavioral and pharmaceutical therapy 11.1. Tinnitus retraining therapy and cognitive behavioral therapy 11.2. Sound therapy and/or music therapy 11.3. Cross-modal stimulation 11.4. Effects of pharmaceutical intervention 11.5. Diet and tinnitus 11.6. Summary Chapter 12. Neurofeedback and neuromodulation: hearing aids, cochlear implants, and transcranial stimulation 12.1. Neurofeedback 12.2. Neuromodulation with hearing aids and cochlear implants 12.3. Noninvasive neuromodulation using transcranial stimulation 12.4. Summary Index