PRINCIPLES OF THERAPEUTICS. Basic Pharmaceutical Principles and the Blood-Brain Barrier. Molecular Therapies for the Nervous System and Muscle. Clinical Trial Methodology, FDA Terminology and Procedures. Placebo Analgesia. Evidence-Based Medicine. Ethical Issues in Neurological Treatment and Clinical Trials. Domestic Violence in Neurological Practice. Palliative Care and Hospice. Stem Cells. PAIN: HEADACHE, SPINE AND LIMB PAIN. Principles of Pain Management. Migraine. Cluster Headaches. Tension-Type Headache. Chronic Daily Headache. Post-Traumatic Headache. Indomethacin-Responsive Headache Syndromes. Giant Cell Arteritis. Headache "Syndromes" in Children and Adolescents. Diagnosis and Treatment of Common Orofacial Pain Conditions. Radicular Limb Pain. Back Pain. Complex Regional Pain Syndrome (Reflex Sympathetic Dystrophy, Cuasalgia, Shoulder-Hand Syndrome). The Treatment of Central Pain. Peripheral (Neuropathic) Pain Disorders. Cancer Pain. Fibromyalgia and Myofascial Pain Syndrome. Pain Disorder. SEIZURE DISORDERS. Classification and Epidemiology of Seizure Disorders: Therapeutic Implications and Importance. Pathophysiology of the Epilepsies. Principles in Epilepsy: Differential Diagnosis and Pharmacotherapy. Antiseizure Drugs. Surgery and Non-Pharmacological Therapies for Epilepsy. Status Epilepticus. The Treatment of Epilepsy in Children and Infants. Seizures and Epilepsy in Women. Imitators of epilepsy. Legal and Regulatory Issues for People with Epilepsy CEREBROVASCULAR DISEASE. Principles of Atherosclerosis and Atherogenesis. Stroke Prevention. Anticoagulant Therapy and Antiplatelet Drugs. Thrombolytic Therapy for Stroke. Asymptomatic Carotid Artery Stenosis. Transient Ischemic Attacks. Management of Patients with Acute Ischemic Stroke. Cardioembolic Stroke. Cerebral Complications after Cardiac Surgery and Cardiac Arrest. Hypoxic-Ischemic Encephalopathy. Treatment of Intracerebral Hemorrhage. Subarachnoid Hemorrhage Due to Cerebral Aneurysms. Cerebral Aneurysms and Vascular Malformations. Unruptured Intracranial Aneurysms. Cervicocephalic Arterial Dissections. Fibromuscular Dysplasia. Venous Disorders. Spinal Cord Vascular Syndromes. Disorders of Coagulation. Antiphospholipid Antibodies and Variants. Hypertensive Encephalopathy. Cerebral Autosomal Dominant Arteriopathy with Subcoritical Infarcts and Leukoencephalopathy (CADASIL). Moyamoya Disease. Stroke in Children. Stroke in Pregnancy. Superficial Siderosis NEURO-ONCOLOGY. A Perspective on Neuro-oncology. Chemotherapy and Antineoplastic Agents. Radiotherapy for CNS Neoplasms: Principles, Technologies and Indications. Surgically Curable Brain Tumors of Adults. Diagnosis and Treatment of Pituitary Tumors. Diffuse Cerebral Gliomas in Adults. Malignant Brain Tumors of Childhood. Germ Cell Tumors and Primary Central Nervous System Lymphoma. Brain Metastases